ROME -- Novak Djokovic cant seem to find any consistency on clay courts. And with the French Open less than 10 days away, he will enter Roland Garros on the back of two early defeats. The top-ranked Serb wasted a chance to serve out the match and was beaten 2-6, 7-5, 6-4 by sixth-seeded Tomas Berdych in the Italian Open quarterfinals Friday. In the semifinals, Berdych will face six-time Rome champion Rafael Nadal, who defeated fellow Spaniard David Ferrer 6-4, 4-6, 6-2. While he struggled at times, Nadal appeared sharper than in his three-set win over Latvian qualifier Ernests Gulbis a day earlier. In the other half of the draw, Roger Federer overcame an early break in the second set to edge rising Polish player Jerzy Janowicz 6-4, 7-6 (2) in a night match at the Foro Italico. Attempting to win this tournament for the first time, Federers next opponent will be Benoit Paire. The 36th-ranked Frenchman routed Marcel Granollers of Spain 6-1, 6-0 to reach his first Masters series semifinal. In the womens tournament, top-ranked Serena Williams rolled past Spanish opponent Carla Suarez Navarro 6-2, 6-0 to extend her winning run to a career-best 22 matches. Williams will next face Romanian qualifier Simona Halep, who rallied past two-time Rome champion Jelena Jankovic 4-6, 6-0, 7-5. Meanwhile, two-time defending champion Maria Sharapova withdrew before her quarterfinal against seventh-seeded Sara Errani due to illness. Errani, the first Italian semifinalist in this tournament since Raffaella Reggi won the 1985 event in Taranto, will face third-seeded Victoria Azarenka, who held off ninth-seeded Sam Stosur 6-4, 1-6, 6-3. Its the second consecutive week that Djokovic has struggled, having also lost to Grigor Dimitrov in the second round of the Madrid Open after being bothered by a right ankle injury. Djokovic said he had been playing pain free this week. Still, he will need to get his game in shape in a hurry with the French Open, the years second Grand Slam, starting May 26. "I know I can play well on clay and so I shouldnt allow myself to have these drops, and lets hope it wont happen for Roland Garros," Djokovic said of the only major he hasnt won. "Im fine. I just lost my rhythm." Djokovic served for the match at 5-3 in the second set, but Berdych ripped a backhand winner that landed on the line on his first break point and won the final four games of the set. "Its a very strange situation," Djokovic said. "I played very well and was two points from winning. Then the entire match changed and I was a different player." Its the first time Berdych has reached the semifinals in eight appearances in Rome, having been eliminated four times in the quarters. The tall Czech took control of the match with his big first serve, and by coming forward to angle shots into the corners to set up easy volleys. Djokovic had trouble returning Berdychs first serve and also complained about the courts surface early on. In the third set, Berdych went ahead with an early break and then shook off some nerves to close the match out on his fourth match point with a big serve out wide that Djokovic could barely get his racket on. As overcast skies gave way to sunshine, the court dried out, favouring Berdychs power game. "I lost the concentration," Djokovic said. "I started playing more defensively. ... He started playing more confidently, stepping into the court and taking advantage of his opportunities." It was only Berdychs second win in 15 career meetings with Djokovic, with his only previous victory coming in the 2010 Wimbledon semifinals. It was also only Berdychs fourth win versus a top-ranked player in 20 attempts, with all three previous wins coming against Federer. "He has been for quite a few years just behind the top four," Djokovic said. "Hes able to play big matches. He has proven that. So (he) is definitely a very dangerous player on any surface with a serve like that." Djokovic was 148-4 when winning the first set since 2011, according to the ATP. Williams had twice won 21 in a row before, although both of those runs came a decade ago, in 2002 and 2003. "Ive been pretty consistent, and pretty healthy -- knock on wood," Williams said. "I feel great -- never felt better." Martina Navratilova established the longest womens win run in the Open Era at 74 matches in 1984. Williams only title here came in 2002, when she beat Justine Henin in the final. That was also the year she won her only French Open title. Last year in Paris, Williams lost in the opening round of a major for the first time, falling to 111th-ranked Virginie Razzano of France. Sharapova said he was struggling with an illness she first contracted last week, when she was runner-up to Williams in Madrid, although she showed no problems Thursday as she beat 16th-seeded Sloane Stephens 6-2, 6-1. 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Julius Randle overcame a scoreless first half and added his sixth double-double in as many games with 14 points and 10 rebounds.The semi-finals of the Guinness PRO12 take place this weekend, and there are a host of ways to watch the games live on Sky Sports. Three Irish provinces have qualified for the last four, along with defending champions Glasgow, and the season is set up for a thrilling finish.The first semi-final takes place on Friday night when Leinster host neighbours Ulster at a sold-out RDS Arena. The teams met last month in Belfast, where Ulster ran out resounding 30-6 winners, but Leinster boast a perfect record in the semi-finals, winning all six games. Connacht were 14-7 winners when they faced Glasgow on May 7 We head west on Saturday as Connacht and Glasgow lock horns in Galway for the second time in 15 days.ddddddddddddPat Lams side edged a nail-biter in difficult conditions at the Sportsground on May 7 to secure a home semi-final.Can Connacht extend their fantastic season and reach the final for the first time or will the Warriors progress to a third successive decider?How can you watch the PRO12 semi-finals on Sky Sports? Fridays coverage from Dublin can be found on Sky Sports 3 HD from 7.30pm. The action switches to Sky Sports 1 HD on Saturday with build-up starting at 6pm.Non-subscribers, meanwhile, will be able to watch the game on NOW TV from £6.99, no contract.And finally, our digital platforms - including skysports.com and the smartphone app - will have all the news and insights both before and after the games, with all the action covered in our live blog. 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